Multiple monitors are a fact of life now, especially with Display tablets like Wacom's Cintiq Pro line. this means you are running into situations where the Pixels per inch of your drawing tablet display (mine is is in the 500 range) and your normal desk top monitors (around 70 dpi). when you try and use the drawing tablet for maximum drawing space and you move UI elements to another monitor they do not resize or scale properly. Currently i have to work around this problem making my wacom run in the same resolution of my normal monitors. Please Implement Per Monitor DPI arewareness so we can use our hardware to its fullest potential.
https://learn.microsoft.com/en-us/windows/win32/hidpi/high-dpi-desktop-application-development-on-windows